Some people disappear from a place you can picture right away: a house, a road, a parking lot, a stretch of woods. But in the case of Edward Sprenkle Dubbs Jr., he seems to vanish somewhere between the parts of his life that made sense on paper.

In January of 1980, a brilliant Columbia doctor went to her home on Nantucket’s remote east end carrying the weight of a life’s work, a possible medical breakthrough, and a kind of urgency the people around her struggled to understand. By the next morning, she was gone.

Homelessness, substance use disorder, and mental health challenges create significant barriers in missing persons cases, often causing individuals to fall through the cracks and their families fighting to get their names and stories heard.